M Amy and Richard reconnect while treating a patient whose diagnosis is not at all what it seems; love becomes the forefront in everyone's mind.

MSC Sonya needs Amy's help treating someone from her past. Richard faces family issues. Jake and TJ discuss ethical concerns about a diagnosis.

M Larsen visits her old home but remembers nothing. She proposes her daughter live with her, but Michael hesitates. Allen sees a demanding patient seeking tests.

M Amy and Sonya endeavour to help a teen in need of a bone marrow transplant and his brother whose own health issues jeopardise disability to donate.

M Amy confronts who she has become after a family tragedy seven years ago. Meanwhile, Sonya and TJ clash over treating a sick Marine.

M Amy is allowed to return to work under very strict guidelines; she teams up with TJ to treat a patient suffering from mysterious liver problems.

M While at the hospital recovering, Amy can't help but insert herself into her roommate's case; all the other doctors and nurses have to adjust to the once formidable chief now being the patient.

MC When Chief of Internal Medicine Dr. Amy Larsen suffers a catastrophic brain injury, her life is turned upside down.