Bono's wife has been airlifted to hospital.
Ali Hewson was vacationing with the U2 singer in Costa Rica when she reportedly fell from a quad bike on the beach and broke her ribs.
It has also been claimed the fashion designer broke a leg in the fall.
Bono, 53, and Ali, 52, who married in 1982 and have four children together, have been staying near Cobano de Puntarenas, on the Pacific coast of the Central American country since February 11.
U2 - which also includes The Edge, Adam Clayton and Larry Mullen - completed their 360 Degree tour, the highest grossing of all time, in 2011, and then took time off to rest and recuperate.
During this time Bono took his family on a round the world trip of the world's most spiritual regions and spent a great deal of time in Central America.
"Because I wasn't busy with the band we kind of went wandering. Once in a lifetime sort of stuff, places like Africa and Central America," he previously said.
"We also went to Jordan and Israel and Peru. It was really great to have time off."
The singer - whose real name is Paul Hewson - recently revealed U2 are working on their 13th studio album, with the working title 10 Reasons To Exist, which will be their first release since 2009's No Line on the Horizon.
"U2 have been back and they're really in fine fettle," he said.
"They're mad for it at the moment and they really want to make a new record. And they don't care if it takes ten years - they don't care if it never happens again, they just want to get it right.
"Within the band we've been calling it 10 Reasons To Exist - but I will tell you we might have at least six of them."