Trail of germs could solve crimes

Published: 3:21PM Tuesday March 16, 2010 Source: Reuters

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People leave more than fingerprints when they touch stuff - they also deposit a tell-tale trail of germs that could help investigators solve crimes, US researchers report.

They were able to map a unique bacterial genetic signature left by nine different people, and say this germy DNA lasted though day-to-day temperature changes, humidity and sunlight.

"Each one of us leaves a unique trail of bugs behind as we travel through our daily lives," Noah Fierer, a researcher at the University of Colorado at Boulder who led the study, says in a statement.

"While this project is still in its preliminary stages, we think the technique could eventually become a valuable new item in the toolbox of forensic scientists," he says.

Researchers have been learning that people are colonized with billions of microbes, both inside and on the body. Studies have shown that these colonies are unique to the individual and even to the place on the body.

Fierer's team wanted to see how much of a trail might be left by these mostly benign bacteria. So they swabbed the computer keyboards of volunteers to show that indeed, each person left not only a trail of unique bacteria, but one that lasted.

In each case, they could show the DNA from the keyboards and computer mice more closely matched DNA from germs on the hands of the owners than they did anybody else's hands.

The technique was about 70 to 90% accurate, Fierer's team reported the Proceedings of the National Academy of Sciences.

The University of Colorado team had previously found that a typical person carries about 150 bacterial species on the hands, and that any two given people only share about 13% of these different species.

"The obvious question then was whether we could identify objects that have been touched by particular individuals," Fierer says.

They also left the bacteria out in the open for two weeks to see if they would break down, but they did not.

"That finding was a real surprise to us," says Fierer.

"We didn't know just how hardy these creatures were."

The researchers were able to do the study because of rapid advances in techniques and equipment for sequencing DNA. A larger project is under way to sequence all the DNA in the human "microbiome" - the collection of bugs that live on the skin, in the nose, hair, ears and digestive tract.

These organisms help digest and metabolize food and may affect skin conditions.

And unlike non-native disease-causing germs, they are not dislodged by standard hygiene.

"Palm surface bacterial communities recover within hours after hand washing," the researchers wrote.

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