Twin wakes and blows raspberry to her carer 

Source: ONE NewsOne of the recently separated conjoined twins with guardian Moira Kelly

It was the moment Moira Kelly had been waiting for all week. Twin Krishna finally awoke from her medically induced coma and blew her guardian a raspberry.

Kelly had said she wouldn't relax until the signature raspberry appeared, indicating the toddler had pulled through lifesaving surgery to separate her from her conjoined twin sister, Trishna.

"Krishna has woken up and I got my raspberry," Ms Kelly told reporters outside the Royal Children's Hospital on Saturday.

A jubilant Kelly said the first raspberry was followed by seven more in quick succession.

The Children First Foundation founder - the twins' legal guardian - said Krishna woke up about 8pm on Friday, three days after the marathon 32-hour operation and more than 24 hours after Trishna.

The Bangladeshi girls, now nearly three years old, were born joined at the head and brought to Australia two years ago by the foundation to undergo surgery at the hospital.

Trishna woke up on Thursday and was soon talking and cuddling Kelly, but Krishna's body had more to adjust to and she spent longer recovering under sedation.

Kelly said she "did a big yelp" when Krishna blew the raspberries.

She then rang members of the medical team who performed the groundbreaking surgery to tell them the good news.

Neurosurgeons Wirginia Maixner and Alison Wray, who toiled over 27 hours at the delicate task of separating the girls' brains, both came into the hospital with wide grins, Kelly said.

"The whole hospital is smiling."

Kelly said more challenges lay ahead for the girls, who are lying side by side in separate cots in intensive care.

"The children are in the ICU, they'll be there for awhile.

"They've certainly got the rehab to get through, but neurologically they are sound."

Kelly said it had been her "dream" to know the twin girls had a mother, after hearing the news a woman claiming to be the mother had come forward.

Lavlee Mollik, 22, handed over her girls to an orphanage in Dhaka only one month after their birth because she and husband Kartik, 35, were unable to care for them, News Ltd newspapers reported on Saturday.

Mollik, speaking through a translator by telephone from Bangladesh, said she was praying for her daughters' safe recovery.

But the couple is unable to care for them, and Mollik wants them to live and be educated in Australia.

"One day when they have become very respected people I want them to call me mother," she said, adding she would like to visit the girls one day.

"It will be the most happy day of my life if I can see them again."

Danielle Noble, the 27-year-old volunteer who found the twins three years ago in the Bangladeshi orphanage, visited them in hospital on Saturday.

"I got to see the girls for the first time today since their separation and it's the most incredible feeling to think that three years ago, this was just a dream," she told reporters.

"Now they are going to have a fantastic life."